The induction of the acrosome reaction in guinea-pig sperm by the divalent metal cation ionophore A23187.
نویسنده
چکیده
The divalent metal cation ionophore A23187 induces an acrosome reaction in guinea-pig sperm which is dependent on external calcium. Examination of this acrosome reaction by electron microscopy shows that it is morphologically normal. The known properties of A23187 and the morphological similarity between the acrosome reaction and the secretory discharges of other secretory cells suggests that the immediate cause of the acrosome reaction is an increase in the cytoplasmic free calcium concentration.
منابع مشابه
P-17: Effect of Calcium Ionophore A23187 on Sperm Hyper-Active Motility Patterns
Background The role of calcium in physiological phenomenona such as sperm acrosome reaction and hyper-activation has been well known. Calcium ionophore A23187 is routinely used for induction of acrosome reaction in mammalians sperm. Therefore, we decided to evaluate the effect of calcium ionophore A23187 on the sperm hyper-active motility patterns. MaterialsAndMethods Ten semen samples from ind...
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ورودعنوان ژورنال:
- Journal of cell science
دوره 32 شماره
صفحات -
تاریخ انتشار 1978